Author: Qifang Bi; Yongsheng Wu; Shujiang Mei; Chenfei Ye; Xuan Zou; Zhen Zhang; Xiaojian Liu; Lan Wei; Shaun A Truelove; Tong Zhang; Wei Gao; Cong Cheng; Xiujuan Tang; Xiaoliang Wu; Yu Wu; Binbin Sun; Suli Huang; Yu Sun; Juncen Zhang; Ting Ma; Justin Lessler; Teijian Feng
Title: Epidemiology and Transmission of COVID-19 in Shenzhen China: Analysis of 391 cases and 1,286 of their close contacts Document date: 2020_3_4
ID: hnx213kp_33
Snippet: Overall, 1286 close contacts were identified for index cases testing positive for SARS-CoV-2 between January 14 and February 9, 2020, with 83% (244/292) of cases having at least one close contact. Ninety-five percent of close contacts were followed 12 days or longer. Ninetyeight tested PCR positive for SARS-CoV-2 infection, and one had presumptive infection. Excluding those with a missing test result, we found that the secondary attack rate was 1.....
Document: Overall, 1286 close contacts were identified for index cases testing positive for SARS-CoV-2 between January 14 and February 9, 2020, with 83% (244/292) of cases having at least one close contact. Ninety-five percent of close contacts were followed 12 days or longer. Ninetyeight tested PCR positive for SARS-CoV-2 infection, and one had presumptive infection. Excluding those with a missing test result, we found that the secondary attack rate was 15.8% (95% CI 12.9,19.4) among household contacts and 10.3% (95%CI 8.4,12.6) overall (these drop to 11.2% and 6.6% if those with missing results are considered to be negative). In multivariable analysis of contact types household contact (OR 6.3, 95% CI 1.5, 26.3) and travelling together (OR 7.1, 95% CI 1.4, 34.9) were significantly associated with infection. Reporting contact occurred "often" was also associated with increased risk of infection (OR 8.8 versus moderate frequency contacts, 95% CI 2.6,30.1).
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