Author: Usami, Yu; Hirose, Katsutoshi; Okumura, Masashi; Toyosawa, Satoru; Sakai, Takayoshi
                    Title: Brief communication: Immunohistochemical detection of ACE2 in human salivary gland  Cord-id: py7rzw87  Document date: 2020_9_28
                    ID: py7rzw87
                    
                    Snippet: The novel, severe acute respiratory syndrome coronavirus (SARSâ€CoVâ€2) was firstly reported in late December of 2019 and subsequently caused a global outbreak. It has been shown that SARSâ€CoVâ€2 uses ACE2 (Angiotensin Converting Enzyme 2) as a cellular receptor for host cell entry through the surface unit of SARSâ€CoV spike glycoprotein. In this brief report, we analyze ACE2 protein expression and localization in human salivary gland, and propose a possible role of saliva in the pathogene
                    
                    
                    
                     
                    
                    
                    
                    
                        
                            
                                Document: The novel, severe acute respiratory syndrome coronavirus (SARSâ€CoVâ€2) was firstly reported in late December of 2019 and subsequently caused a global outbreak. It has been shown that SARSâ€CoVâ€2 uses ACE2 (Angiotensin Converting Enzyme 2) as a cellular receptor for host cell entry through the surface unit of SARSâ€CoV spike glycoprotein. In this brief report, we analyze ACE2 protein expression and localization in human salivary gland, and propose a possible role of saliva in the pathogenesis of Coronavirus disease 2019 (COVIDâ€19).
 
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