Selected article for: "lung tissue and significant disease"
Author: Ibrahim, Abdulrahman; Ibrahim, Ahmed; Parimon, Tanyalak
Title: Diagnostic and Therapeutic Applications of Extracellular Vesicles in Interstitial Lung Diseases
  • Cord-id: cw14g6et
  • Document date: 2021_1_7
    • ID: cw14g6et
    Snippet: Interstitial lung diseases (ILDs) are chronic irreversible pulmonary conditions with significant morbidity and mortality. Diagnostic approaches to ILDs are complex and multifactorial. Effective therapeutic interventions are continuously investigated and explored with substantial progress, thanks to advances in basic understanding and translational efforts. Extracellular vesicles (EVs) offer a new paradigm in diagnosis and treatment. This leads to two significant implications: new disease biomark
    Document: Interstitial lung diseases (ILDs) are chronic irreversible pulmonary conditions with significant morbidity and mortality. Diagnostic approaches to ILDs are complex and multifactorial. Effective therapeutic interventions are continuously investigated and explored with substantial progress, thanks to advances in basic understanding and translational efforts. Extracellular vesicles (EVs) offer a new paradigm in diagnosis and treatment. This leads to two significant implications: new disease biomarker discovery that enables reliable diagnosis and disease assessment and the development of regenerative medicine therapeutics that target fibroproliferative processes in diseased lung tissue. In this review, we discuss the current understanding of the role of diseased tissue-derived EVs in the development of interstitial lung diseases, the utility of these EVs as diagnostic and prognostic tools, and the existing therapeutic utility of EVs. Furthermore, we review the potential therapeutic application of EVs derived from various cellular sources.

    Search related documents:
    Co phrase search for related documents
    • accurate diagnosis and liver cirrhosis: 1, 2
    • accurate diagnosis and liver transplantation: 1
    • activating protein and acute lung injury: 1
    • activation kinase and acute lung injury: 1, 2, 3
    • activation kinase and liver cirrhosis: 1
    • active area and acute lung injury: 1
    • active area and liver cirrhosis: 1, 2
    • acute lung injury and adjunctive therapy: 1, 2, 3
    • acute lung injury and liver cirrhosis: 1, 2, 3, 4
    • acute lung injury and liver transplantation: 1, 2
    • adjunctive therapy and liver transplantation: 1