Author: Wang, Wei; Song, Zhigang; Guan, Wencai; Liu, Yi; Zhang, Xiaonan; Xu, Lei; Li, Jianhua; Yuan, Zhenghong; Hu, Yunwen
Title: PCR for Detection of Oseltamivir Resistance Mutation in Influenza A(H7N9) Virus Cord-id: f8xf8746 Document date: 2014_5_25
ID: f8xf8746
Snippet: Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.
Document: Sensitive molecular techniques are needed for rapid detection of the R292K oseltamivir-resistant mutant of influenza A(H7/N9) virus strain to monitor its transmission and guide antiviral treatment. We developed a real-time reverse transcription PCR and single nucleotide polymorphism probes to differentiate this mutant strain in mixed virus populations in human specimens.
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