Author: M. Shaminur Rahman; M. Nazmul Hoque; M. Rafiul Islam; Salma Akter; A. S. M. Rubayet-Ul-Alam; Mohammad Anwar Siddique; Otun Saha; Md. Mizanur Rahaman; Munawar Sultana; M. Anwar Hossain
Title: Epitope-based chimeric peptide vaccine design against S, M and E proteins of SARS-CoV-2 etiologic agent of global pandemic COVID-19: an in silico approach Document date: 2020_3_31
ID: 0yqyclxk_45
Snippet: To further characterize the immunogenicity and immune response profile of the CoV-691 RMEN, in silico immune simulations were conducted using the C-ImmSim server 692 The red, cyan, and yellow colored regions represent the potential antigenic domains predicted by the IEDB analysis resource Elipro analysis. GalaxyWEB-GalaxyPepDock-server followed by the refinement using GalaxyRefineComplex and free energy (ΔG) of each complex was determined in PRO.....
Document: To further characterize the immunogenicity and immune response profile of the CoV-691 RMEN, in silico immune simulations were conducted using the C-ImmSim server 692 The red, cyan, and yellow colored regions represent the potential antigenic domains predicted by the IEDB analysis resource Elipro analysis. GalaxyWEB-GalaxyPepDock-server followed by the refinement using GalaxyRefineComplex and free energy (ΔG) of each complex was determined in PRODIGY server. Ribbon structures represent HLA alleles and stick structures represent the respective epitopes. Light color represents the templates to which the alleles and epitopes structures were built. Further information on molecular docking analysis is also available in Supplementary Data 1.
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