Author: Angelo Virgilio Paradiso; Simona De Summa; Daniela Loconsole; Vito Procacci; Anna Sallustio; Francesca Centrone; Nicola Silvestris; Vito Cafagna; Giuseppe De Palma; Antonio Tufaro; Vito Garrisi; Maria Chironna
Title: Clinical meanings of rapid serological assay in patients tested for SARS-Co2 RT-PCR Document date: 2020_4_6
ID: ilxd0ih9_14
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.20052183 doi: medRxiv preprint considered positive at molecular screening if all the three genes were detected. Moreover, the WHO Real-time rRT-PCR protocol was used to confirm the presence of SARS-CoV-2 (https://www.who.int/docs/default-source/coronaviruse/uscdcrt-pcrp a n e l -f o r -d e t e c t i o n -i n s t r u .....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.03.20052183 doi: medRxiv preprint considered positive at molecular screening if all the three genes were detected. Moreover, the WHO Real-time rRT-PCR protocol was used to confirm the presence of SARS-CoV-2 (https://www.who.int/docs/default-source/coronaviruse/uscdcrt-pcrp a n e l -f o r -d e t e c t i o n -i n s t r u c t i o n s . p d f ? s f v r s n = 3 a a 0 7 9 3 4 _ 2 ) . SARS-CoV-2 rapid IgG-IgM Test SARS-CoV-2 rapid IgG-IgM Viva-Diag TM Test combined antibody test kit designed and manufactured by Jiangsu Medomics Medical Technologies.The test is based on a lateral flow qualitative immunoassay for the rapid determination of the presence or absence of both anti-SARS-CoV-2-IgM and anti-SARS-CoV-2-IgG in human specimens (whole blood, serum, and plasma). A surface antigen from SARS-CoV-2 which can specifically bind to SARS-CoV-2 antibodies (including both IgM and IgG) is conjugated to colloidal gold nanoparticles and sprayed on conjugation pads. The SARS-CoV-2 rapid IgG-IgM combined antibody test strip has two mouse anti-human monoclonal antibodies (anti-IgG and anti-IgM) stripped on two separated test lines.
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