A Case of New Onset Diabetes and Severe Diabetes Ketoacidosis in a Patient With COVID-19

Patel, Latika; Ayad, Sarah; Rayad, Mohammad Nabil; Gergis, Kirolos; Ejikeme, Chidinma; Talpur, Afrah; Abdelazeem, Basel; Eckman, Ari

Diabetic ketoacidosis (DKA) is a significant complication of poorly controlled diabetes. In diabetics, it typically occurs due to insulin deficiency resulting in lipolysis and subsequent ketone body formation and acidosis. The emergence of the COVID-19 infection has been associated with several complications, with the most prominent being pulmonary and cardiovascular-related. However, in some cases, patients with COVID-19 infection present with diabetic ketoacidosis. The pathophysiology of DKA in COVID-19 infection is different and currently not completely understood. The manifestation of DKA in COVID-19 patients is associated with increased severity of mortality and length of stay in these patients. Here, we describe a patient with no past medical history who presented with COVID-19 symptoms and was found to be in DKA. This case report highlights the possible underlying pathophysiology associated with this complication.