Author: Udaondo, Zulema; Matilla, Miguel A.
Title: Mining for novel antibiotics in the age of antimicrobial resistance Cord-id: g0ojjf3h Document date: 2020_9_2
ID: g0ojjf3h
Snippet: The misuse of antimicrobials is causing an alarming increase in the appearance of antibioticâ€resistant microorganisms. In this context, the identification of novel antibiotics against new targets and with low rates of resistance development is a major global challenge. In this article, we highlight a number of recent articles that exploit a variety of in vitro, in vivo and in silico stateâ€ofâ€theâ€art approaches to identify and develop new antimicrobials. Rapid progress in this research fi
Document: The misuse of antimicrobials is causing an alarming increase in the appearance of antibioticâ€resistant microorganisms. In this context, the identification of novel antibiotics against new targets and with low rates of resistance development is a major global challenge. In this article, we highlight a number of recent articles that exploit a variety of in vitro, in vivo and in silico stateâ€ofâ€theâ€art approaches to identify and develop new antimicrobials. Rapid progress in this research field will be crucial to combating a global health problem, antimicrobial resistance, that is expected to be the leading cause of death by 2050.
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