Selected article for: "high titer and infectious titer"

Author: Heilingloh, Christiane Silke; Aufderhorst, Ulrich Wilhelm; Schipper, Leonie; Dittmer, Ulf; Witzke, Oliver; Yang, Dongliang; Zheng, Xin; Sutter, Kathrin; Trilling, Mirko; Alt, Mira; Steinmann, Eike; Krawczyk, Adalbert
Title: Susceptibility of SARS-CoV-2 to UV Irradiation
  • Cord-id: ddouxod1
  • Document date: 2020_8_4
  • ID: ddouxod1
    Snippet: The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/ml was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1048 mJ/cm(2). UVA exposure demonstrated only a weak effect on virus inactivation over 15 min
    Document: The coronavirus SARS-CoV-2 pandemic became a global health burden. We determined the susceptibility of SARS-CoV-2 to irradiation with ultraviolet light. The virus was highly susceptible to ultraviolet light. A viral stock with a high infectious titer of 5 × 10(6) TCID(50)/ml was completely inactivated by UVC irradiation after nine minutes of exposure. The UVC dose required for complete inactivation was 1048 mJ/cm(2). UVA exposure demonstrated only a weak effect on virus inactivation over 15 minutes. Hence, inactivation of SARS-CoV-2 by UVC irradiation constitutes a reliable method for disinfection purposes in health care facilities and for preparing SARS-CoV-2 material for research purpose.

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