Selected article for: "negative test probability and zero positive"

Author: Daniel B Larremore; Bailey K Fosdick; Kate M Bubar; Sam Zhang; Stephen M Kissler; C. Jessica E. Metcalf; Caroline Buckee; Yonatan Grad
Title: Estimating SARS-CoV-2 seroprevalence and epidemiological parameters with uncertainty from serological surveys
  • Document date: 2020_4_20
  • ID: c4cs14ja_103
    Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04.15.20067066 doi: medRxiv preprint observing n negative tests is (1 − θ) n . Setting this equal to 0.05 and solving for θ, we find θ = 1 − .05 1/n ≈ 3/n, where the approximation is based on the power series representation of the exponential function. Now, let's consider what happens if sensitivity and specificity are not equal to .....
    Document: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04.15.20067066 doi: medRxiv preprint observing n negative tests is (1 − θ) n . Setting this equal to 0.05 and solving for θ, we find θ = 1 − .05 1/n ≈ 3/n, where the approximation is based on the power series representation of the exponential function. Now, let's consider what happens if sensitivity and specificity are not equal to one and again zero positive tests are observed. The probability of a negative test is then

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