Author: Yoluç, Yasemin; Ammann, Gregor; Barraud, Pierre; Jora, Manasses; Limbach, Patrick A; Motorin, Yuri; Marchand, Virginie; Tisné, Carine; Borland, Kayla; Kellner, Stefanie
Title: Instrumental analysis of RNA modifications. Cord-id: dokgrz5t Document date: 2021_2_22
ID: dokgrz5t
Snippet: Organisms from all domains of life invest a substantial amount of energy for the introduction of RNA modifications into nearly all transcripts studied to date. Instrumental analysis of RNA can focus on the modified residues and reveal the function of these epitranscriptomic marks. Here, we will review recent advances and breakthroughs achieved by NMR spectroscopy, sequencing, and mass spectrometry of the epitranscriptome.
Document: Organisms from all domains of life invest a substantial amount of energy for the introduction of RNA modifications into nearly all transcripts studied to date. Instrumental analysis of RNA can focus on the modified residues and reveal the function of these epitranscriptomic marks. Here, we will review recent advances and breakthroughs achieved by NMR spectroscopy, sequencing, and mass spectrometry of the epitranscriptome.
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