Selected article for: "nucleic acid and potential pathogen"
Author: Wang, Xinjie; Shang, Xiaoyun; Huang, Xingxu
Title: Next-generation pathogen diagnosis with CRISPR/Cas-based detection methods
  • Cord-id: 6xfefyg3
  • Document date: 2020_7_20
    • ID: 6xfefyg3
    Snippet: Ideal methods for detecting pathogens should be sensitive, specific, rapid, cost-effective and instrument-free. Conventional nucleic acid pathogen detection strategies, mostly PCR-based techniques, have various limitations, such as expensive equipment, reagents and skilled performance. Recently, CRISPR/Cas-based methods have burst onto the scene, with the potential to power the pathogen detection field. Here we introduce these unique methods and discuss its hurdles and promises.
    Document: Ideal methods for detecting pathogens should be sensitive, specific, rapid, cost-effective and instrument-free. Conventional nucleic acid pathogen detection strategies, mostly PCR-based techniques, have various limitations, such as expensive equipment, reagents and skilled performance. Recently, CRISPR/Cas-based methods have burst onto the scene, with the potential to power the pathogen detection field. Here we introduce these unique methods and discuss its hurdles and promises.

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