Author: Welsh, Raymond M.; Fujinami, Robert S.
Title: Pathogenic epitopes, heterologous immunity and vaccine design Cord-id: 6y0xvp37 Document date: 2007_1_1
ID: 6y0xvp37
Snippet: Substantial research has been directed towards the development of a new generation of vaccines that are based on the inclusion of immunogenic epitopes in recombinant vectors. Here we examine the evidence that under certain conditions immunogenic epitopes can do more harm than good and might therefore be considered pathogenic. We suggest that the specific removal of such pathogenic epitopes from vaccines might increase their prophylactic potential, while minimizing the risk of side-effects from v
Document: Substantial research has been directed towards the development of a new generation of vaccines that are based on the inclusion of immunogenic epitopes in recombinant vectors. Here we examine the evidence that under certain conditions immunogenic epitopes can do more harm than good and might therefore be considered pathogenic. We suggest that the specific removal of such pathogenic epitopes from vaccines might increase their prophylactic potential, while minimizing the risk of side-effects from vaccine use.
Search related documents:
Co phrase search for related documents- low frequency and lung transplantation: 1
- low frequency and lymphocytic choriomeningitis virus: 1
- lung pathology and lymphoid tissue: 1
- lung pathology and m1 influenza: 1, 2
Co phrase search for related documents, hyperlinks ordered by date