Author: Chi Heem Wong; Kien Wei Siah; Andrew W Lo
Title: Estimating Probabilities of Success of Clinical Trials for Vaccines and Other Anti-Infective Therapeutics Document date: 2020_4_14
ID: fnrm6a79_44
Snippet: It remains to be seen if more non-industry-sponsored research can alleviate the issue. Our study shows that only 6.8% (SE: 1.0%) and 8.2% (SE: 0.6%) of non-industry-sponsored vaccines and non-vaccine infectious disease development programs transition from phase 1 to approval, respectively. However, this may be a result of selection bias: promising vaccine and therapeutics initiated in non-industry settings are often pursued in conjunction with in.....
Document: It remains to be seen if more non-industry-sponsored research can alleviate the issue. Our study shows that only 6.8% (SE: 1.0%) and 8.2% (SE: 0.6%) of non-industry-sponsored vaccines and non-vaccine infectious disease development programs transition from phase 1 to approval, respectively. However, this may be a result of selection bias: promising vaccine and therapeutics initiated in non-industry settings are often pursued in conjunction with industry-sponsored sponsors, whereas commercially less promising projects are more likely to be pursued by non-profit organizations.
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