Author: Darwish, Hoda Salah; Habash, Mohamed Yasser; Habash, Waleed Yasser
Title: Chest computed tomography imaging features in patients with coronavirus disease 2019 (COVID-19) Cord-id: fhebzsi5 Document date: 2021_5_4
ID: fhebzsi5
Snippet: OBJECTIVE: To analyze computed tomography (CT) features of symptomatic patients with coronavirus disease 2019 (COVID-19). METHODS: Ninety-five symptomatic patients with COVID-19 confirmed by reverse-transcription polymerase chain reaction from 1 May to 14 July 2020 were retrospectively enrolled. Follow-up CT findings and their distributions were analyzed and compared from symptom onset to late-stage disease. RESULTS: Among all patients, 15.8% had unilateral lung disease and 84.2% had bilateral d
Document: OBJECTIVE: To analyze computed tomography (CT) features of symptomatic patients with coronavirus disease 2019 (COVID-19). METHODS: Ninety-five symptomatic patients with COVID-19 confirmed by reverse-transcription polymerase chain reaction from 1 May to 14 July 2020 were retrospectively enrolled. Follow-up CT findings and their distributions were analyzed and compared from symptom onset to late-stage disease. RESULTS: Among all patients, 15.8% had unilateral lung disease and 84.2% had bilateral disease with slight right lower lobe predilection (47.4%). Regarding lesion density, 49.4% of patients had pure ground glass opacity (GGO) and 50.5% had GGO with consolidation. Typical early-stage patterns were bilateral lesions in 73.6% of patients, diffuse lesions (41.0%), and GGO (65.2%). Pleural effusion occurred in 13.6% and mediastinal lymphadenopathy in 11.5%. During intermediate-stage disease, 47.4% of patients showed GGO as the disease progressed; however, consolidation was the predominant finding (52.6%). CONCLUSION: COVID-19 pneumonia manifested on lung CT scans with bilateral, peripheral, and right lower lobe predominance and was characterized by diffuse bilateral GGO progressing to or coexisting with consolidation within 1 to 3 weeks. The most frequent CT lesion in the early, intermediate, and late phases was GGO. Consolidation appeared in the intermediate phase and gradually increased, ending with reticular and lung fibrosis-like patterns.
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