Author: Bergmann, Cornelia C.; Lane, Thomas E.; Stohlman, Stephen A.
Title: Coronavirus infection of the central nervous system: host–virus stand-off Cord-id: s16po29r Document date: 2006_1_1
ID: s16po29r
Snippet: Several viruses infect the mammalian central nervous system (CNS), some with devastating consequences, others resulting in chronic or persistent infections associated with little or no overt pathology. Coronavirus infection of the murine CNS illustrates the contributions of both the innate immune response and specific host effector mechanisms that control virus replication in distinct CNS cell types. Despite T-cell-mediated control of acute virus infection, host regulatory mechanisms, probably d
Document: Several viruses infect the mammalian central nervous system (CNS), some with devastating consequences, others resulting in chronic or persistent infections associated with little or no overt pathology. Coronavirus infection of the murine CNS illustrates the contributions of both the innate immune response and specific host effector mechanisms that control virus replication in distinct CNS cell types. Despite T-cell-mediated control of acute virus infection, host regulatory mechanisms, probably designed to protect CNS integrity, contribute to the failure to eliminate virus. Distinct from cytolytic effector mechanisms expressed during acute infection, non-lytic humoral immunity prevails in suppressing infectious virus during persistence.
Search related documents:
Co phrase search for related documents- activation induce and acute infection: 1, 2, 3, 4, 5
- activation induce and acute infection response: 1
- activation induce and acute phase: 1
- activation induce and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- activation induce and acute virus: 1, 2, 3
- activation induce and adaptive immune response: 1, 2, 3, 4
- activation induce apoptosis and acute respiratory syndrome: 1
- activation induce apoptosis and acute virus: 1
- acute disease and adaptive immune component: 1
- acute disease and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute disease and adaptive immune response activation: 1, 2
- acute infection and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute infection and adaptive immune response activation: 1
- acute infection control and adaptive immune response: 1
- acute infection response and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8
- acute phase and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8
- acute phase and adaptive immune response activation: 1
- acute respiratory syndrome and adaptive immune response: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory syndrome and adaptive immune response activation: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date