Author: Daniel B Larremore; Bailey K Fosdick; Kate M Bubar; Sam Zhang; Stephen M Kissler; C. Jessica E. Metcalf; Caroline Buckee; Yonatan Grad
Title: Estimating SARS-CoV-2 seroprevalence and epidemiological parameters with uncertainty from serological surveys Document date: 2020_4_20
ID: c4cs14ja_57
Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04.15.20067066 doi: medRxiv preprint However, imperfect specificity and sensitivity require that we modify this formula. For convenience, in the remainder of this supplemental text, we will use: u ≡ Pr(test is positive | seronegative) = 1 − specificity v ≡ Pr(test is negative | seropositive) = 1 − sensitivity Using this notation, the.....
Document: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.04.15.20067066 doi: medRxiv preprint However, imperfect specificity and sensitivity require that we modify this formula. For convenience, in the remainder of this supplemental text, we will use: u ≡ Pr(test is positive | seronegative) = 1 − specificity v ≡ Pr(test is negative | seropositive) = 1 − sensitivity Using this notation, the probability that a single test returns a positive result, given u, v, and the true seroprevalence θ, is
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