Selected article for: "dna sequencing analysis and sequencing analysis"
Author: Niimi, Miyako; Masuda, Taisuke; Kaihatsu, Kunihiro; Kato, Nobuo; Nakamura, Shota; Nakaya, Takaaki; Arai, Fumihito
Title: Virus purification and enrichment by hydroxyapatite chromatography on a chip
  • Cord-id: wph0lnzk
  • Document date: 2014_10_1
    • ID: wph0lnzk
    Snippet: The spread of infectious diseases has become a global health concern. In order to diagnose infectious diseases quickly and accurately, next-generation DNA sequencing techniques for genetic analysis of infectious viruses have been developed rapidly. However, it takes a very long time to pretreat clinical samples for genetic analysis using next-generation sequencers. We have therefore developed a microfluidic chromatography chip that can purify and enrich viruses in a sample using hydroxyapatite p
    Document: The spread of infectious diseases has become a global health concern. In order to diagnose infectious diseases quickly and accurately, next-generation DNA sequencing techniques for genetic analysis of infectious viruses have been developed rapidly. However, it takes a very long time to pretreat clinical samples for genetic analysis using next-generation sequencers. We have therefore developed a microfluidic chromatography chip that can purify and enrich viruses in a sample using hydroxyapatite particles packed in a micro-column. We demonstrated the purification of virus from a mixture of virus and FBS protein, and enrichment of the virus using this novel microfluidic chip.

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