Author: Pinna, Graziano
Title: Sex and COVID-19: A protective role for reproductive steroids Cord-id: eatlugrm Document date: 2020_11_9
ID: eatlugrm
Snippet: Evidence shows COVID-19-induced symptom severity and mortality are more frequent in men than in women suggesting sex steroids may play a protective role. Female reproductive steroids, estrogen and progesterone and its metabolite, allopregnanolone are anti-inflammatory, reshape competence of immune cells, stimulate antibody production and promote proliferation and respiratory epithelial cell repair suggesting they may protect against COVID-19 symptoms.
Document: Evidence shows COVID-19-induced symptom severity and mortality are more frequent in men than in women suggesting sex steroids may play a protective role. Female reproductive steroids, estrogen and progesterone and its metabolite, allopregnanolone are anti-inflammatory, reshape competence of immune cells, stimulate antibody production and promote proliferation and respiratory epithelial cell repair suggesting they may protect against COVID-19 symptoms.
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