Author: Daniel B Larremore; Bailey K Fosdick; Kate M Bubar; Sam Zhang; Stephen M Kissler; C. Jessica E. Metcalf; Caroline Buckee; Yonatan Grad
Title: Estimating SARS-CoV-2 seroprevalence and epidemiological parameters with uncertainty from serological surveys Document date: 2020_4_20
ID: c4cs14ja_20
Snippet: probability of a positive test in subpopulation i given test sensitivity (se), test specificity (sp), and subpopulation seroprevalence θ i , and x i is the the relative importance of subpopulation i to the quantity to be estimated. When that quantity is overall seroprevalence, x i is the fraction of the population in subpopulation i; when that quantity is total infections or R eff , x i can be derived from the structure of the model itself (see .....
Document: probability of a positive test in subpopulation i given test sensitivity (se), test specificity (sp), and subpopulation seroprevalence θ i , and x i is the the relative importance of subpopulation i to the quantity to be estimated. When that quantity is overall seroprevalence, x i is the fraction of the population in subpopulation i; when that quantity is total infections or R eff , x i can be derived from the structure of the model itself (see Methods). If subpopulation prevalence estimates θ i are unknown, sample allocation based solely on x i is recommended.
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