Author: Chi Heem Wong; Kien Wei Siah; Andrew W Lo
Title: Estimating Probabilities of Success of Clinical Trials for Vaccines and Other Anti-Infective Therapeutics Document date: 2020_4_14
ID: fnrm6a79_26
Snippet: In contrast to vaccines, which are intended to prevent disease, a number of alternatives have been developed to treat-and, in some cases, cure-patients afflicted with an infectious disease. According to our dataset, 3,851 and 2,978 industry-sponsored and non-industry-sponsored non-vaccine drug development programs, respectively, have been initiated in the area of infectious disease (see Figure 4 ). The top three diseases with the greatest number .....
Document: In contrast to vaccines, which are intended to prevent disease, a number of alternatives have been developed to treat-and, in some cases, cure-patients afflicted with an infectious disease. According to our dataset, 3,851 and 2,978 industry-sponsored and non-industry-sponsored non-vaccine drug development programs, respectively, have been initiated in the area of infectious disease (see Figure 4 ). The top three diseases with the greatest number of industry-sponsored drug development programs are respiratory infections (21.8%), HIV (15.7%) and hepatitis C virus, or HCV (14.1%). Together, they comprise 51.6% of all industry-sponsored non-vaccine development programs. Nonindustry anti-infectious-disease drug development programs focus on treating respiratory infections (20.5%), HIV (13.9%), and bacteria skin infection (12.1%).
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