Selected article for: "present study and retrospective study"
Author: Nicola F Fletcher; Luke W Meredith; Emma L Tidswell; Steven R Bryden; Daniel Gonçalves-Carneiro; Yasmin Chaudhry; Claire Shannon-Lowe; Michael A Folan; Daniella A Lefteri; Marieke Pingen; Dalan Bailey; Clive S McKimmie; Alan W Baird
Title: A novel antiviral formulation inhibits a range of enveloped viruses.
  • Document date: 2020_3_30
    • ID: nly9vojr_62
    Snippet: activity. To investigate the components of ViroSAL that are responsible for its activity, we evaluated individual components of ViroSAL (Caprylate, DPPG, Lecithin and Kolliphor), at concentrations equivalent to amounts present in 2% ViroSAL, together with 2% ViroSAL and 10ng/ml IFN-y as a positive antiviral control. Only Caprylate (caprylic acid) had a significant effect on VSV-G pseudovirus entry to Vero cells ( Figure 4B ). However, 2% ViroSAL .....
    Document: activity. To investigate the components of ViroSAL that are responsible for its activity, we evaluated individual components of ViroSAL (Caprylate, DPPG, Lecithin and Kolliphor), at concentrations equivalent to amounts present in 2% ViroSAL, together with 2% ViroSAL and 10ng/ml IFN-y as a positive antiviral control. Only Caprylate (caprylic acid) had a significant effect on VSV-G pseudovirus entry to Vero cells ( Figure 4B ). However, 2% ViroSAL fully neutralized viral entry, indicating that caprylic acid within the ViroSAL formulation was more potent as an antiviral than caprylic acid alone.

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