Author: Herman, A.; Matthews, M.; Mairlot, M.; Nobile, L.; Fameree, L.; Jacquet, L.â€M.; Baeck, M.
Title: Drug reaction with eosinophilia and systemic symptoms syndrome in a patient with COVIDâ€19 Cord-id: xdfl659q Document date: 2020_8_13
ID: xdfl659q
Snippet: Skin rashes associated with COVID-19 include eruptions induced by drugs prescribed for management of this infection. We report a case of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a patient with COVID-19. A 50-year-old man was admitted to the intensive care unit for pneumonia with acute respiratory distress syndrome. COVID-19 was confirmed by positive RT-PCR SARS-CoV-2 on nasopharyngeal swabs and later by positive IgM and IgG antibodies against SARS-CoV-2 (114,5 AU
Document: Skin rashes associated with COVID-19 include eruptions induced by drugs prescribed for management of this infection. We report a case of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome in a patient with COVID-19. A 50-year-old man was admitted to the intensive care unit for pneumonia with acute respiratory distress syndrome. COVID-19 was confirmed by positive RT-PCR SARS-CoV-2 on nasopharyngeal swabs and later by positive IgM and IgG antibodies against SARS-CoV-2 (114,5 AU/mL). In the context of fever >38,5°C, nine days after admission, the patient developed a generalized maculopapular rash on more than 70% of his body surface area with oedema of hands and face (Fig.1). Azithromycin and hydroxychloroquine had been initiated 18 and 17 days respectively prior to the skin eruption.
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