On Key Epidemiological Metrics during Infectious Disease Outbreaks

Battista, Hern'an De; Garc'ia-Cl'ua, Jos'e; Nunez, Sebasti'an; Inthamoussou, Fernando; Ingenier'ia, Fabricio Garelli Grupo de Control Aplicado GCA-LEICI. Facultad de; CONICET, Universidad Nacional de La Plata -; Argentina,

In this work, we review the figures used to characterize an epidemic outbreak most. Particular attention is drawn to epidemic spreading at time-varying transition rates. A time-varying SIR-like model is used to describe the epidemic dynamics, from which closed equations relating parameters and key quantities like reproduction ratio and doubling time are derived. The definition and computation of these metrics are revisited in the context of the general solution to the time-varying model dynamics, focusing on the similarities and differences with the time-invariant case. Further, the prediction of these metrics, that is of the disease evolution, as response to different scenarios is also investigated.