Author: Li, Jie; Pavlov, Ivan; Laffey, John G.; Roca, Oriol; Mirza, Sara; Perez, Yonatan; McNicholas, Bairbre; Cosgrave, David; Vines, David; Tavernier, Elsa; Ehrmann, Stephan
Title: Meta-trial of awake prone positioning with nasal high flow therapy: Invitation to join a pandemic collaborative research effort Cord-id: e8hdx4u2 Document date: 2020_7_24
ID: e8hdx4u2
Snippet: • Awake prone positioning is a promising intervention to improve patient's oxygenation and likely to reduce the need for intubation. Despite reports of its use during the COVID-19 pandemic, controlled evidence is lacking. • A meta-trial, with harmonized inclusion and outcome criteria and a global interim analysis plan, may enable to get a high level of evidence within the short period of time required by the pandemic, through performing a prospective meta-analysis of the generated data acros
Document: • Awake prone positioning is a promising intervention to improve patient's oxygenation and likely to reduce the need for intubation. Despite reports of its use during the COVID-19 pandemic, controlled evidence is lacking. • A meta-trial, with harmonized inclusion and outcome criteria and a global interim analysis plan, may enable to get a high level of evidence within the short period of time required by the pandemic, through performing a prospective meta-analysis of the generated data across countries. • Clinicians and researchers around the world are invited to join the “Meta-trial of awake prone positioning with nasal high flow therapy†project by contacting the core investigator group: [email protected].
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