Selected article for: "function structure and positive sense"
Author: Wolff, Georg; Melia, Charlotte E.; Snijder, Eric J.; Bárcena, Montserrat
Title: Double-Membrane Vesicles as Platforms for Viral Replication
  • Cord-id: h95mtir4
  • Document date: 2020_6_11
    • ID: h95mtir4
    Snippet: Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a variety of fascinating ways. A striking example of this is the remodelling of intracellular membranes into specialized structures that support the replication of positive-sense ssRNA (+RNA) viruses infecting eukaryotes. These distinct forms of virus-induced structures include double-membrane vesicles (DMVs), found during viral infections as diverse and notorious as those of coronaviruses, enteroviruses, no
    Document: Viruses, as obligate intracellular parasites, exploit cellular pathways and resources in a variety of fascinating ways. A striking example of this is the remodelling of intracellular membranes into specialized structures that support the replication of positive-sense ssRNA (+RNA) viruses infecting eukaryotes. These distinct forms of virus-induced structures include double-membrane vesicles (DMVs), found during viral infections as diverse and notorious as those of coronaviruses, enteroviruses, noroviruses, or hepatitis C virus. Our understanding of these DMVs has evolved over the past 15 years thanks to advances in imaging techniques and modern molecular biology tools. In this article, we review contemporary understanding of the biogenesis, structure, and function of virus-induced DMVs as well as the open questions posed by these intriguing structures.

    Search related documents:
    Co phrase search for related documents
    • active replication complex and acute respiratory syndrome: 1, 2
    • active site and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • active site and additional function: 1
    • acute respiratory syndrome and additional benefit: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • acute respiratory syndrome and additional factor: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • acute respiratory syndrome and additional function: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • acute respiratory syndrome and additional requirement: 1, 2, 3, 4
    • acute respiratory syndrome and live cell imaging: 1, 2, 3, 4, 5, 6, 7, 8
    • acute respiratory syndrome and live cell monitor: 1