Author: Farr, Ellen; Wolfe, Alexis R.; Deshmukh, Swati; Rydberg, Leslie; Soriano, Rachna; Walter, James M.; Boon, Andrea J.; Wolfe, Lisa F.; Franz, Colin K.
Title: Diaphragm dysfunction in severe COVIDâ€19 as determined by neuromuscular ultrasound Cord-id: gw2gj3r8 Document date: 2021_7_11
ID: gw2gj3r8
Snippet: Many survivors from severe coronavirus disease 2019 (COVIDâ€19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe postâ€COVIDâ€19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickne
Document: Many survivors from severe coronavirus disease 2019 (COVIDâ€19) suffer from persistent dyspnea and fatigue long after resolution of the active infection. In a cohort of 21 consecutive severe postâ€COVIDâ€19 survivors admitted to an inpatient rehabilitation hospital, 16 (76%) of them had at least one sonographic abnormality of diaphragm muscle structure or function. This corresponded to a significant reduction in diaphragm muscle contractility as represented by thickening ratio (muscle thickness at maximal inspiration/endâ€expiration) for the postâ€COVIDâ€19 compared to nonâ€COVIDâ€19 cohorts. These findings may shed new light on neuromuscular respiratory dysfunction as a contributor to prolonged functional impairments after hospitalization for postâ€COVIDâ€19.
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