Author: Saraogi, Punit; Kaushik, Vaibhav; Chogale, Ritesh; Chavan, Sneha; Gode, Vaishali; Mhaskar, Sudhakar
Title: Virgin coconut oil as prophylactic therapy against alcohol damage on skin in COVID times Cord-id: ehhtjtiv Document date: 2021_6_18
ID: ehhtjtiv
Snippet: BACKGROUND: Increased frequency of using alcoholâ€based hand sanitizers (ABHS) by consumers during COVID times have resulted in increased incidences of skin issues on palms. OBJECTIVE: (1) To quantify skin damage with increased usage frequency of ABHS by consumers and (2) To evaluate Virgin Coconut Oil (VCO) as natural prophylactic agent to counter the adverse effects. METHODS: Inâ€home usage study was carried out with 60 volunteers for a 15â€day intervention—Control Group: 6 applications p
Document: BACKGROUND: Increased frequency of using alcoholâ€based hand sanitizers (ABHS) by consumers during COVID times have resulted in increased incidences of skin issues on palms. OBJECTIVE: (1) To quantify skin damage with increased usage frequency of ABHS by consumers and (2) To evaluate Virgin Coconut Oil (VCO) as natural prophylactic agent to counter the adverse effects. METHODS: Inâ€home usage study was carried out with 60 volunteers for a 15â€day intervention—Control Group: 6 applications per day of ABHS and Test Group: Overnight VCO use (6–8 drops) followed by 6× usage per day of ABHS. This leg included dermatological evaluation and WHO Selfâ€Assessment Scale for skin health. Another leg of measurement included nonâ€invasive instrumental study (Moisture & TEWL Probes, Tape Strip for protein content and IR spectroscopy for protein & lipid content) on forearm of 12 subjects (25–60 years age) with and without VCO application and repeated alcohol exposure. RESULTS: Inâ€home usage study established consumer experiencing skin protective effect of VCO in the context of ABHS onslaught. 25% increase in perceived moisture content was recorded for VCO users, using WHO Selfâ€Assessment Scale. Instrumental studies confirmed an increase in TEWL and decrease in lipids & protein content. Overnight VCO application resists the extraction which builds up with repeated application. CONCLUSIONS: Current work provides evidence of compromised hand skin barrier with ABHS daily usage. Overnight VCO application helps prepare the skin for next day alcohol use. Based on the findings, a regimen of overnight VCO application on hands as a natural prophylactic is recommended.
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