Author: Mishra, Nischay; Huang, Xi; Joshi, Shreyas; Guo, Cheng; Ng, James; Thakkar, Riddhi; Wu, Yongjian; Dong, Xin; Li, Qianlin; Pinapati, Richard; Sullivan, Eric; Caciula, Adrian; Tokarz, Rafal; Briese, Thomas; Lu, Jiahai; Lipkin, W. Ian
Title: Immunoreactive peptide maps of SARS-CoV-2 and other human coronaviruses Cord-id: ei95g2vq Document date: 2020_8_13
ID: ei95g2vq
Snippet: Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity to the human coronaviruses (HCoV) SARS-CoV-2, SARS-CoV-1, MERS-CoV, OC43, 229E, HKU1, and NL63. Here we report the identification of humoral immune responses to SARS-CoV-2 and other HCoV peptides that can be used to detect asymptomatic, mild and, severe SARS-CoV-2 infections, and may enable the discovery of biomarkers for immunity following infection or vaccination.
Document: Serodiagnosis of SARS-CoV-2 infection is impeded by immunological cross-reactivity to the human coronaviruses (HCoV) SARS-CoV-2, SARS-CoV-1, MERS-CoV, OC43, 229E, HKU1, and NL63. Here we report the identification of humoral immune responses to SARS-CoV-2 and other HCoV peptides that can be used to detect asymptomatic, mild and, severe SARS-CoV-2 infections, and may enable the discovery of biomarkers for immunity following infection or vaccination.
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