Author: El-Said, Waleed A.; Alâ€Bogami, Abdullah S.; Alshitari, Wael; El-Hady, Deia A.; Saleh, Tamer S.; El-Mokhtar, Mohamed A.; Choi, Jeong-Woo
Title: Electrochemical Microbiosensor for Detecting COVID-19 in a Patient Sample Based on Gold Microcuboids Pattern Cord-id: whhmk30b Document date: 2021_8_9
ID: whhmk30b
Snippet: As continues increasing the COVID-19 infections, there is an urgent need for developing fast, simple, selective, and accurate COVID-19 biosensors. A highly uniform gold (Au) microcuboid pattern was used as a microelectrode that allowed monitoring a small analyte. The electrochemical biosensor was used to monitor the COVID-19 S protein within a concentration range from 100 to 5 pmol L(−1); it showed a lower detection limit of 276 fmol L(−1). Finally, the developed COVID-19 sensor was used to
Document: As continues increasing the COVID-19 infections, there is an urgent need for developing fast, simple, selective, and accurate COVID-19 biosensors. A highly uniform gold (Au) microcuboid pattern was used as a microelectrode that allowed monitoring a small analyte. The electrochemical biosensor was used to monitor the COVID-19 S protein within a concentration range from 100 to 5 pmol L(−1); it showed a lower detection limit of 276 fmol L(−1). Finally, the developed COVID-19 sensor was used to detect a positive sample from a human patient obtained through a nasal swab; the results were confirmed using the PCR technique. The results showed that the SWV technique showed high sensitivity towards detecting COVID-19 and good efficiency for detecting COVID-19 in a positive human sample.
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