Author: Zhang, Yang; Li, Haichao; Zhang, Jian; Cao, Yedi; Zhao, Xue; Yu, Nan; Gao, Ying; Ma, Jing; Zhang, Hong; Zhang, Junqing; Guo, Xiaohui; Liu, Xinmin
Title: The Clinical Characteristics and Outcomes of Diabetes Mellitus and Secondary Hyperglycaemia Patients with Coronavirus Disease 2019: a Singleâ€center, Retrospective, Observational Study in Wuhan Cord-id: xv7xonw6 Document date: 2020_5_14
ID: xv7xonw6
Snippet: AIMS: Since the pandemic outbreak of COVIDâ€19, limited information is available on diabetic patients with COVIDâ€19. MATERIALS AND METHODS: We retrospectively analysed 166 COVIDâ€19 patients at Tongji Hospital (Wuhan) from February 8 to March 21, 2020. Clinical characteristics and outcomes (as of April 4, 2020) were compared among control (group 1), secondary hyperglycaemia (group 2: no diabetes history, FPG levels ≥7.0 mmol/L once and HbA1c values <6.5%) and diabetic (group 3) patients. R
Document: AIMS: Since the pandemic outbreak of COVIDâ€19, limited information is available on diabetic patients with COVIDâ€19. MATERIALS AND METHODS: We retrospectively analysed 166 COVIDâ€19 patients at Tongji Hospital (Wuhan) from February 8 to March 21, 2020. Clinical characteristics and outcomes (as of April 4, 2020) were compared among control (group 1), secondary hyperglycaemia (group 2: no diabetes history, FPG levels ≥7.0 mmol/L once and HbA1c values <6.5%) and diabetic (group 3) patients. RESULTS: Compared to group 1, groups 2 and 3 had higher rates of leukocytosis, neutrophilia, lymphocytopenia, eosinopenia, and levels of sCRP, ferritin and dâ€dimer (P < 0.05 for all). Group 2 patients have higher levels of LDH, prevalence of liver dysfunction and increased ILâ€8 than those in group 1, a higher prevalence of increased ILâ€8 was found in group 2 than in group 3 (P < 0.05 for all). The proportions of critical patients in groups 2 and 3 were significantly higher compared to group 1 (38.1%, 32.8% vs. 9.5%, P < 0.05 for both). Groups 2 and 3 had significantly longer hospital stays than group 1, which was nearly one week longer. The composite outcomes risks were 5.47 (1.56–19.82) and 2.61 (0.86–7.88) times greater in group 2 and 3 than in group 1. CONCLUSIONS: Hyperglycemia in both diabetes and secondary hyperglycemia patients with COVIDâ€19 may indicate poor prognoses. There were differences between secondary hyperglycemia and diabetes patients. We recommend that clinicians pay more attention to the blood glucose status of COVIDâ€19 patients, even those not diagnosed with diabetes before admission.
Search related documents:
Co phrase search for related documents- a1c hba1c level and logistic regression: 1
- a1c hba1c level and logistic regression analysis: 1
- accepted article and acute respiratory syndrome: 1, 2, 3, 4, 5
- accepted article and admission patient: 1
- accepted article and logistic regression: 1
Co phrase search for related documents, hyperlinks ordered by date