Assessment of COVID-19 vaccine hesitancy among Zimbabweans: A rapid national survey

Mundagowa, P. T.; Tozivepi, S. N.; Chiyaka, E. T.; Mukora-Mutseyekwa, F.; Makurumidze, R.

Background: To minimize the devastating effects of the coronavirus disease 2019 (COVID 19) pandemic, scientists hastily developed a vaccine. However, the scaling up of the vaccination is likely to be hindered by the widespread social media misinformation. We, therefore, conducted a study to assess the COVID 19 vaccine hesitancy among Zimbabweans. Methods: We conducted a descriptive online cross-sectional survey using a self administered questionnaire among adults. The questionnaire assessed willingness to be vaccinated; sociodemographic characteristics, individual attitudes and perceptions, effectiveness, and safety of the vaccine. Multivariable logistic regression analysis was utilized to examine the independent factors associated with vaccine uptake. Results: We analyzed data for 1168 participants, the age range of 19 to 89 years with the majority being females (57.5%). Half (49.9%) of the participants reported that they would accept the COVID 19 vaccine. The majority were uncertain about the effectiveness of the vaccine (76.0%) and its safety (55.0%). About half lacked trust in the government s ability to ensure the availability of an effective vaccine and 61.0% mentioned that they would seek advice from a healthcare worker to vaccinate. Age 55 years and above [vs 18 to 25 years Adjusted Odds Ratio (AOR): 2.04, 95% Confidence Interval (CI): 1.07 to 3.87], chronic disease [vs no chronic disease AOR: 1.72, 95%CI: 1.32 to 2.25], males [vs females AOR: 1.84, 95%CI: 1.44 to 2.36] and being a healthcare worker [vs not being a health worker AOR: 1.73, 95%CI: 1.34 to 2.24] were associated with increased likelihood to vaccinate. History of COVID 19 infection [vs no history - AOR: 0.45, 95%CI: 0.25 to 0.81) and rural residence [vs urban - AOR: 0.64, 95%CI: 0.40 to 1.01] were associated with reduced likelihood to vaccinate. Conclusion: We found half of the participants willing to vaccinate against COVID-19. The majority lacked trust in the government and were uncertain about vaccine effectiveness and safety. The policymakers should consider targeting geographical and demographic groups which were unlikely to vaccinate with vaccine information, education, and communication to improve uptake.