Author: Wanda J. Lyon; Zachary K. Smith; Brian Grier; James Baldwin; Clarise R. Starr
Title: Evaluating an Upper Respiratory Disease Panel on the Portable MinION Sequencer Document date: 2018_10_5
ID: 3begdfx2_2
Snippet: Next-generation sequencing (NGS) technologies are now capable of providing a whole genome sequence or metagenomics for a wide range of organisms [16, 36] . NGS is being applied with increasing frequency in clinical microbiology laboratories to detect and characterize pathogens, thereby replacing the currently used Sanger sequencing methods [3, 39] . Sanger sequencing has been a reliable and robust method that has served clinical laboratories well.....
Document: Next-generation sequencing (NGS) technologies are now capable of providing a whole genome sequence or metagenomics for a wide range of organisms [16, 36] . NGS is being applied with increasing frequency in clinical microbiology laboratories to detect and characterize pathogens, thereby replacing the currently used Sanger sequencing methods [3, 39] . Sanger sequencing has been a reliable and robust method that has served clinical laboratories well for over several decades; however, it is labor intensive, slow, and not easily adapted for processing large genomes or large samples sets.
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