Author: Jiao-Mei Huang; Syed Sajid Jan; Xiaobin Wei; Yi Wan; Songying Ouyang
Title: Evidence of the Recombinant Origin and Ongoing Mutations in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Document date: 2020_3_17
ID: fw4pmaoc_14
Snippet: Based on amino acid and genome sequences analysis and comparison, our results suggest that SARS-CoV-2 is a recombinant virus between bat and pangolin coronaviruses, and the recombination event has been occurred in spike protein genes. Our finding suggest that pangolin is the most possible intermediate SARS-CoV-2 reservoir, which may have given rise to cross-species transmission to humans. These new findings suggest further research to investigate.....
Document: Based on amino acid and genome sequences analysis and comparison, our results suggest that SARS-CoV-2 is a recombinant virus between bat and pangolin coronaviruses, and the recombination event has been occurred in spike protein genes. Our finding suggest that pangolin is the most possible intermediate SARS-CoV-2 reservoir, which may have given rise to cross-species transmission to humans. These new findings suggest further research to investigate pangolin as a SARS-CoV-2 reservoir. Another important outcome of our analysis is the genetic mutations and evolution of SARS-CoV-2 as it spread globally. These findings are very significant for controlling the SARS-CoV-2 pandemic.
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