Selected article for: "maximum likelihood and phylogenetic tree"
Author: Jiao-Mei Huang; Syed Sajid Jan; Xiaobin Wei; Yi Wan; Songying Ouyang
Title: Evidence of the Recombinant Origin and Ongoing Mutations in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2)
  • Document date: 2020_3_17
    • ID: fw4pmaoc_3
    Snippet: To determine the evolutionary relationship of the SARS-CoV-2, phylogenetic analysis was performed on whole genomic sequences of different CoVs from various hosts. The Maximum-likelihood (ML) phylogenetic tree is shown in Figure 1 , which illustrates four main groups representing four genera of CoVs, alpha, beta, gamma, and delta. In the phylogenetic tree, strains of SARS-CoV-2 (red colored) are cluster together and belong to the genera Betacorona.....
    Document: To determine the evolutionary relationship of the SARS-CoV-2, phylogenetic analysis was performed on whole genomic sequences of different CoVs from various hosts. The Maximum-likelihood (ML) phylogenetic tree is shown in Figure 1 , which illustrates four main groups representing four genera of CoVs, alpha, beta, gamma, and delta. In the phylogenetic tree, strains of SARS-CoV-2 (red colored) are cluster together and belong to the genera Betacoronavirus. Among Beta-CoVs, SARS-CoV, Civet SARS CoV, Bat SARS-like CoVs, bat/RaTG13 CoV, and SARS-CoVs-2 clustered together forming a discrete clade from MERS-CoVs. The clade is further divided into two branches and one of the branches comprises all SARS-CoV-2 strains clustered together with Bat/Yunnan/RaTG13 CoV forming a monophyletic group. Bat/Yunnan/RaTG13 exhibited ~96% genomic similarity with SARS-CoV-2. This specifies that SARS-CoV-2 is closely related to Bat/Yunnan/RaTG13 CoV.

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