Author: Hondermarck, Hubert; Bartlett, Nathan W.; Nurcombe, Victor
Title: The role of growth factor receptors in viral infections: An opportunity for drug repurposing against emerging viral diseases such as COVIDâ€19? Cord-id: hf05zl0u Document date: 2020_4_11
ID: hf05zl0u
Snippet: Growth factor receptors are known to be involved in the process of viral infection. Many viruses not only use growth factor receptors to physically attach to the cell surface and internalize, but also divert receptor tyrosine kinase signaling in order to replicate. Thus, repurposing drugs that have initially been developed to target growth factor receptors and their signaling in cancer may prove to be a fast track to effective therapies against emerging new viral infections, including the corona
Document: Growth factor receptors are known to be involved in the process of viral infection. Many viruses not only use growth factor receptors to physically attach to the cell surface and internalize, but also divert receptor tyrosine kinase signaling in order to replicate. Thus, repurposing drugs that have initially been developed to target growth factor receptors and their signaling in cancer may prove to be a fast track to effective therapies against emerging new viral infections, including the coronavirus disease 19 (COVIDâ€19).
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