Author: Ting Ding; Jinjin Zhang; Tian Wang; Pengfei Cui; Zhe Chen; Jingjing Jiang; Su Zhou; Jun Dai; Bo Wang; Suzhen Yuan; Wenqing Ma; Lingwei Ma; Yueguang Rong; Jiang Chang; Xiaoping Miao; Xiangyi Ma; Shixuan Wang
Title: A Multi-hospital Study in Wuhan, China:Protective Effects of Non-menopause and Female Hormones on SARS-CoV-2 infection Document date: 2020_3_30
ID: lplodn60_44
Snippet: Sex-specific disease outcomes following virus infections are attributed to sexdependent production of steroid hormones, different copy numbers of immune response X-linked genes, and the presence of disease susceptibility genes in males and females 13 . Our data showed that E2 and AMH are positively correlated with the disease severity. E2 is primarily produced in ovaries and considered as the most prevalent and potent form of circulating estrogen.....
Document: Sex-specific disease outcomes following virus infections are attributed to sexdependent production of steroid hormones, different copy numbers of immune response X-linked genes, and the presence of disease susceptibility genes in males and females 13 . Our data showed that E2 and AMH are positively correlated with the disease severity. E2 is primarily produced in ovaries and considered as the most prevalent and potent form of circulating estrogen. Estrogens are thought to protect non-menopausal women from hepatitis C virus and other pathogens 14, 15 . Also, All rights reserved. No reuse allowed without permission. the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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