Author: Emily R Adams; Rekha Anand; Monique I Andersson; Kathryn Auckland; J Kenneth Baillie; Eleanor Barnes; John Bell; Tamsin Berry; Sagida Bibi; Miles Carroll; Senthil Chinnakannan; Elizabeth Clutterbuck; Richard J Cornall; Derrick W Crook; Thushan De Silva; Wanwisa Dejnirattisai; Kate E Dingle; Christina Dold; David W Eyre; Helen Farmer; Sarah J Hoosdally; Alistair Hunter; Katie Jeffrey; Paul Klenerman; Julian Knight; Clarice Knowles; Andrew J Kwok; Ullrich Leuschner; Chang Liu; Cesar Lopez-Camacho; Philippa C Matthews; Hannah McGivern; Alexander J Mentzer; Jonathan Milton; Juthathip Mongkolsapaya; Shona C Moore; Marta S Oliveira; Fiona Pereira; Timothy Peto; Rutger J Ploeg; Andrew Pollard; Tessa Prince; David J Roberts; Justine K Rudkin; Gavin R Screaton; Malcolm G Semple; Donal T Skelly; Elliot Nathan Smith; Julie Staves; David Stuart; Piyada Supasa; Tomas Surik; Pat Tsang; Lance Turtle; A Sarah Walker; Beibei Wang; Charlotte Washington; Nicholas Watkins; James Whitehouse; Sally Beer; Robert Levin; Alexis Espinosa; Dominique Georgiou; Jose Carlos Martinez Garrido; Hannah Thraves; Elena Perez Lopez; Maria del Rocio Fernandez Mendoza; Alberto Jose Sobrino Diaz; Veronica Sanchez
Title: Evaluation of antibody testing for SARS-Cov-2 using ELISA and lateral flow immunoassays Document date: 2020_4_20
ID: 5trox1i5_16
Snippet: Forty positive (RT-PCR-confirmed SARS-CoV-2 infection) and 50 designated negative (prepandemic) plasma samples were tested by ELISA to characterise antibody profiles. Negative samples had median optical density (OD) for IgM of -0.0001 (arbitrary units) (range -0.14 to 0.06) and for IgG -0.01 (range -0.38 to 0.26). The median IgM reading in 40 positive samples was 0.18 (range -0.008 to 1.13; Kruskal-Wallis p<0.001 vs. negative) and IgG median 3.0 .....
Document: Forty positive (RT-PCR-confirmed SARS-CoV-2 infection) and 50 designated negative (prepandemic) plasma samples were tested by ELISA to characterise antibody profiles. Negative samples had median optical density (OD) for IgM of -0.0001 (arbitrary units) (range -0.14 to 0.06) and for IgG -0.01 (range -0.38 to 0.26). The median IgM reading in 40 positive samples was 0.18 (range -0.008 to 1.13; Kruskal-Wallis p<0.001 vs. negative) and IgG median 3.0 (range -0.2 to 3.5; p<0.001).
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