Author: Yong Gao; Yi Yuan; Tuan Tuan Li; Wu Xiao Wang; Yong Xiu Li; Ang Li; Feng Ming Han
Title: Evaluation the auxiliary diagnosis value of antibodies assays for detection of novel coronavirus (SARS-Cov-2) causing an outbreak of pneumonia (COVID-19) Document date: 2020_3_30
ID: 8mx5kowl_22
Snippet: Firstly, the detectability of antibodies assays in patients with undetectable viral RNA in their respiratory tract specimens were analyzed. As the results shown in Table 2 and Table 3 , combined use of the tests of RNA and antibodies assay at the same time was able to improve the sensitivities of pathogenic-diagnosis for SARS-CoV-2 infection, especially for the throat swabs group at the later stage of illness.Then, we further analyzed the antibod.....
Document: Firstly, the detectability of antibodies assays in patients with undetectable viral RNA in their respiratory tract specimens were analyzed. As the results shown in Table 2 and Table 3 , combined use of the tests of RNA and antibodies assay at the same time was able to improve the sensitivities of pathogenic-diagnosis for SARS-CoV-2 infection, especially for the throat swabs group at the later stage of illness.Then, we further analyzed the antibodies test data of cases with undetectable viral RNA in their throat swabs specimens at the early stage of illness. Most of them were shown to be IgM/IgG seropositive after 7 days of negative nucleic acid test results (IgM + 47.1%, IgG + 91.1%), suggesting an auxiliary diagnosis value of antibodies assays.
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