Author: Focosi, Daniele; Franchini, Massimo
Title: Potential use of convalescent plasma for SARS-CoV-2 prophylaxis and treatment in immunocompromised and vulnerable populations Cord-id: i85fj1zj Document date: 2021_5_27
ID: i85fj1zj
Snippet: INTRODUCTION: : The ongoing SARS-CoV-2 pandemic is a serious threat for the health of immunocompromised patients. Among neutralizing antibody-based therapeutics, convalescent plasma containing polyclonal anti-SARS-CoV-2 immunoglobulins has promising results in both congenital and iatrogenic immunodeficiencies in oncohematological and transplant patients. AREAS COVERED: : This article discusses case reports, case series and controlled studies detailing the efficacy of convalescent plasma in immun
Document: INTRODUCTION: : The ongoing SARS-CoV-2 pandemic is a serious threat for the health of immunocompromised patients. Among neutralizing antibody-based therapeutics, convalescent plasma containing polyclonal anti-SARS-CoV-2 immunoglobulins has promising results in both congenital and iatrogenic immunodeficiencies in oncohematological and transplant patients. AREAS COVERED: : This article discusses case reports, case series and controlled studies detailing the efficacy of convalescent plasma in immunocompromised patients. EXPERT OPINION: : Convalescent plasma, when administered at high neutralizing antibody titers, is a safe and effective treatment for frail immunocompromised patients. Genetic monitoring of refractory patients is recommended to intercept intra-host emergence of SARS-CoV-2 variants.
Search related documents:
Co phrase search for related documents- active chemotherapy and acute leukemia: 1, 2, 3
- active chemotherapy and acute myeloid leukemia: 1, 2
- active chemotherapy and lymphocytic leukemia: 1, 2, 3
- active chemotherapy and lymphoma patient: 1
- acute leukemia and liver transplant: 1
- acute leukemia and long term benefit: 1
- acute leukemia and longitudinal study: 1, 2, 3
- acute leukemia and lung transplant: 1, 2
- acute leukemia and lymphoblastic leukemia: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72, 73, 74
- acute leukemia and lymphocytic leukemia: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
- acute leukemia and lymphoma patient: 1, 2, 3
- acute leukemia and mab monoclonal antibody: 1
- acute lymphoblastic leukemia and liver transplant: 1
- acute lymphoblastic leukemia and longitudinal study: 1
Co phrase search for related documents, hyperlinks ordered by date