Author: Maciej F Boni; Philippe Lemey; Xiaowei Jiang; Tommy Tsan-Yuk Lam; Blair Perry; Todd Castoe; Andrew Rambaut; David L Robertson
Title: Evolutionary origins of the SARS-CoV-2 sarbecovirus lineage responsible for the COVID-19 pandemic Document date: 2020_3_31
ID: h2uc7ria_16
Snippet: Using the most conservative approach to identifying a non-recombinant genomic region (NRR1), SARS-CoV-2 forms a sister lineage with RaTG13, with genetically related cousin lineages of coronavirus sampled in pangolins in Guangdong and Guangxi provinces ( Figure 2 ). Given that these pangolin viruses are ancestral to the progenitor of the RaTG13/SARS-CoV-2 lineage, it is more likely that they are also picking up viruses from bats. While pangolins c.....
Document: Using the most conservative approach to identifying a non-recombinant genomic region (NRR1), SARS-CoV-2 forms a sister lineage with RaTG13, with genetically related cousin lineages of coronavirus sampled in pangolins in Guangdong and Guangxi provinces ( Figure 2 ). Given that these pangolin viruses are ancestral to the progenitor of the RaTG13/SARS-CoV-2 lineage, it is more likely that they are also picking up viruses from bats. While pangolins could be acting as intermediate hosts for bat viruses to get into humansthey develop severe respiratory disease (Lie et al., 2019) and commonly come into contact with people as they are trafficked in large numbers for consumption and use in Chinese medicine -pangolin infection is not a requirement for bat viruses to cross into humans.
Search related documents:
Co phrase search for related documents- bat virus and conservative approach: 1
- bat virus and genomic region: 1, 2
- bat virus and human cross: 1, 2, 3, 4, 5, 6, 7, 8
- bat virus and intermediate host: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
- bat virus and large number: 1, 2, 3, 4, 5, 6, 7, 8
- bat virus and pangolin virus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- bat virus and people contact: 1
- bat virus and respiratory disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28
- bat virus and SARS lineage: 1, 2, 3, 4, 5, 6, 7, 8, 9
- bat virus and severe respiratory disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
- bat virus and sister lineage: 1
- bat virus intermediate host and intermediate host: 1
- bat virus intermediate host and respiratory disease: 1
- bat virus intermediate host and severe respiratory disease: 1
- chinese medicine and large number: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18
- chinese medicine and people contact: 1, 2
- chinese medicine and respiratory disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55
- chinese medicine and severe respiratory disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33
- chinese medicine infection and respiratory disease: 1, 2, 3
Co phrase search for related documents, hyperlinks ordered by date