Author: Ria Lassaunière; Anders Frische; Zitta B Harboe; Alex CY Nielsen; Anders Fomsgaard; Karen A Krogfelt; Charlotte S Jørgensen
Title: Evaluation of nine commercial SARS-CoV-2 immunoassays Document date: 2020_4_10
ID: 8cg5yj20_2
Snippet: Accurate diagnosis of COVID-19 is essential, not only to ensure appropriate patient care but also to facilitate identification of SARS-CoV-2 infected people, including asymptomatic carriers, who need to be isolated to limit virus spread. The WHO recommends nucleic acid detection of SARS-CoV-2 in respiratory samples for the diagnosis of COVID-19. Unfortunately, in the face of the rapidly growing epidemics worldwide, an increased demand for diagnos.....
Document: Accurate diagnosis of COVID-19 is essential, not only to ensure appropriate patient care but also to facilitate identification of SARS-CoV-2 infected people, including asymptomatic carriers, who need to be isolated to limit virus spread. The WHO recommends nucleic acid detection of SARS-CoV-2 in respiratory samples for the diagnosis of COVID-19. Unfortunately, in the face of the rapidly growing epidemics worldwide, an increased demand for diagnostic tests has led to a critical shortage in operational material for respiratory sample collection and within the molecular diagnostic workflow [3, 4] . This impedes rapid large scale testing, a necessity for controlling the epidemic. Moreover, the heterogeneity of respiratory sample material and anatomical location of sample collection, for example throat swab, saliva or endotracheal aspirate, affect the sensitivity of SARS-CoV-2 viral nucleic acid testing [5, 6] . Overall, there is an urgent need to identify alternative diagnostic means.
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