Selected article for: "heart disease and limited sample size"
Author: Shitao Rao; Alexandria Lau; Hon-Cheong So
Title: Exploring diseases/traits and blood proteins causally related to expression of ACE2, the putative receptor of 2019-nCov: A Mendelian Randomization analysis
  • Document date: 2020_3_8
    • ID: myh73pe6_51
    Snippet: On the other hand, we also wish to highlight some results could be false negatives. The main reason for false negatives is the limited sample size of GTEx, and that for some exposure traits, the number of instruments available may be small. For example, in our analysis, we do not find evidence of hypertension or blood pressure, history of coronary heart disease and stroke to be casually linked to ACE2 expression, although patients with severe inf.....
    Document: On the other hand, we also wish to highlight some results could be false negatives. The main reason for false negatives is the limited sample size of GTEx, and that for some exposure traits, the number of instruments available may be small. For example, in our analysis, we do not find evidence of hypertension or blood pressure, history of coronary heart disease and stroke to be casually linked to ACE2 expression, although patients with severe infections have been reported to be enriched for these comorbidities.

    Search related documents:
    Co phrase search for related documents
    • blood pressure and false negative: 1, 2, 3, 4
    • blood pressure and heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • blood pressure and main reason: 1, 2
    • blood pressure and sample size: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • blood pressure hypertension and coronary heart disease: 1, 2, 3
    • blood pressure hypertension and heart disease: 1, 2, 3, 4, 5, 6, 7, 8
    • blood pressure hypertension and sample size: 1, 2
    • coronary heart disease and false negative: 1
    • coronary heart disease and heart disease: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • coronary heart disease and sample size: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • false negative and heart disease: 1, 2, 3, 4
    • false negative and main reason: 1, 2
    • false negative and sample size: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • GTEx sample size and sample size: 1, 2
    • heart disease and sample size: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • main reason and sample size: 1, 2, 3