Evaluation of the clinical characteristics of suspected or confirmed cases of COVID-19 during home care with isolation: A new retrospective analysis based on O2O

Hui Xu; Sufang Huang; Shangkun Liu; Juan Deng; Bo Jiao; Ling Ai; Yaru Xiao; Li Yan; Shusheng Li

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.26.20028084 doi: medRxiv preprint Nevertheless, we found that the hospitalized patients were significantly older than the non-hospitalized patients, which was consistent with previous findings. 12, 14 We also had an interesting age-related observation in a father-daughter patient pair (patient 1 and patient 2). We found that although the father became ill first, the daughter had much severe symptoms except chest tightness and dyspnea than her father during the early stage of the disease. However, while the daughter's symptoms gradually improved over time, the father's chest tightness, dyspnea and previously latent symptoms worsened. Interestingly, the imaging features of these two patients were different from their respective clinical manifestations. The CT results of the daughter showed marked progression, whereas those of the father indicated minimal change. At the time of manuscript submission, the CT results of the daughter have significantly improved, and her symptoms have already disappeared. The patient is currently waiting for her second nucleic acid test results and may be discharged if the results turn out negative. On the other hand, the father is still experiencing mild dyspnea with no significant absorption by CT and must continue to be hospitalized for treatment.