Evolutionary origins of epidemic potential among human RNA viruses

Lu Lu; Liam Brierley; Gail Robertson; Feifei Zhang; Samantha Lycett; Donald Smith; Margo Chase-Topping; Peter Simmonds; Mark Woolhouse

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/771394 doi: bioRxiv preprint Table S1 . Numbers of estimated transitions between human-infective/transmissible (IT) levels 1, 2 and 3/4 across all genera (N=39) compared for three methodologies: 1) counts of the number of internal node changes, transitions, observed from discrete traits analysis* and 2) number of expected transitions (mean) from Markov jumps, both with input trees generated by Bayesian interference; 3) number of expected transitions (mean) from the parsimony reconstruction method with input trees generated using maximum likelihood methods. *Transitions are identified as changes in the most probable IT level between adjacent nodes (see Fig. 1 ). Details of level transitions with posterior supports are given in Data Files 2 and 3.