Author: Liang, Meng-yuan; Chen, Ping; He, Miao; Tang, Jian; Li, Hui; He, Xin-liang; Zhou, Ya-ya; Feng, Si-wei; Xue, Yu-e; Liu, Yao; Ma, Yan-ling; Zhang, Jian-chu
Title: Corticosteroids Treatment of Patients with Coronavirus Disease 2019: A Propensity Score Matching Study Cord-id: gq599egh Document date: 2021_2_13
ID: gq599egh
Snippet: The role of corticosteroids in the treatment of Coronavirus disease 2019 (COVID-19) is controversial. In the present study, we evaluated the effects of adjuvant corticosteroids treatment on the outcome of patients with COVID-19 (n=966), using Propensity Score Matching to adjust for potential differences between the corticosteroids group (n=289) and the non-corticosteroids group (n=677). Analysis of data without adjusting differences in baseline characteristics indicated that the proportion of me
Document: The role of corticosteroids in the treatment of Coronavirus disease 2019 (COVID-19) is controversial. In the present study, we evaluated the effects of adjuvant corticosteroids treatment on the outcome of patients with COVID-19 (n=966), using Propensity Score Matching to adjust for potential differences between the corticosteroids group (n=289) and the non-corticosteroids group (n=677). Analysis of data without adjusting differences in baseline characteristics indicated that the proportion of mechanical ventilation and the mortality was higher in the corticosteroids treatment group in total or severe/critical patients. The duration of viral shedding was longer in the non-corticosteroids treatment group in total or general/mild patients. After adjusting the difference between the corticosteroids and non-corticosteroids treatment group, the analysis revealed that the use of corticosteroids had no effect on the duration of viral shedding, in-hospital mortality or 28-day mortality. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11596-021-2313-6) contains supplementary material, which is available to authorized users.
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