Selected article for: "high mutation rate and long term"
Author: Lin, Qianyu; Ji, Xiang; Wu, Feng; Ma, Lan
Title: Conserved Sequence Analysis of Influenza A Virus HA Segment and Its Application in Rapid Typing
  • Cord-id: g4kigrx9
  • Document date: 2021_7_23
    • ID: g4kigrx9
    Snippet: The high mutation rate of the influenza A virus hemagglutinin segment poses great challenges to its long-term effective testing and subtyping. Our conserved sequence searching method achieves high-specificity conserved sequences on H1–H9 subtypes. In addition, PCR experiments show that primers based on conserved sequences can be used in influenza A virus HA subtyping. Conserved sequence-based primers are expected to be long-term, effective subtyping tools for influenza A virus HA.
    Document: The high mutation rate of the influenza A virus hemagglutinin segment poses great challenges to its long-term effective testing and subtyping. Our conserved sequence searching method achieves high-specificity conserved sequences on H1–H9 subtypes. In addition, PCR experiments show that primers based on conserved sequences can be used in influenza A virus HA subtyping. Conserved sequence-based primers are expected to be long-term, effective subtyping tools for influenza A virus HA.

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