Selected article for: "Dynamic Light scattering and Light scattering"
Author: Popp, Corinna; Schramm, Philipp; Wagner, Ralf; Peterhoff, David; Battle, Christopher; Kleusch, Christian; Plach, Maximilian G.
Title: Multi-parameter formulation development for an HIV-vaccine protein with direct validation of epitope binding integrity and stoichiometry
  • Cord-id: g5a259y8
  • Document date: 2020_11_30
    • ID: g5a259y8
    Snippet: Vaccines are on the front line-of-defense against infectious diseases, ranging from threats we are familiar with, including polio, tuberculosis, or HIV, to novel and emerging threats such as SARS-CoV-2. Successful development of new protein-based vaccines requires sophisticated and efficient development of storage and formulation conditions. Here we demonstrate the combined power of 2bind’s sophisticated buffer matrix FORMOscreen® and NanoTemper Technologies’ novel Prometheus Panta high-thr
    Document: Vaccines are on the front line-of-defense against infectious diseases, ranging from threats we are familiar with, including polio, tuberculosis, or HIV, to novel and emerging threats such as SARS-CoV-2. Successful development of new protein-based vaccines requires sophisticated and efficient development of storage and formulation conditions. Here we demonstrate the combined power of 2bind’s sophisticated buffer matrix FORMOscreen® and NanoTemper Technologies’ novel Prometheus Panta high-throughput Dynamic Light Scattering/Nano Differential Scanning Fluorimetry instrument. We show that this combination can comprehensively improve critical biophysical parameters for the HIV-1 vaccine BG505-SOSIP and find the optimal formulation condition with unmatched efficiency.

    Search related documents:
    Co phrase search for related documents
    • accelerated process and acute respiratory: 1, 2
    • acute respiratory and additional oxidative stress: 1, 2
    • acute respiratory and additional peak: 1, 2
    • acute respiratory and long term effect: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • acute respiratory and long term storage: 1, 2, 3, 4, 5
    • acute respiratory and long term storage production: 1
    • acute respiratory and low sample: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19
    • acute respiratory and low sample consumption: 1, 2
    • acute respiratory and low temperature: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29