Selected article for: "activation system and liver specific"
Author: Skevaki, Chrysanthi; Fragkou, Paraskevi C.; Cheng, Chongsheng; Xie, Min; Renz, Harald
Title: Laboratory characteristics of patients infected with the novel SARS-CoV-2 virus
  • Cord-id: jpwf55l6
  • Document date: 2020_6_21
    • ID: jpwf55l6
    Snippet: A subgroup of COVID-19 patients develop very severe disease with requirement for ICU treatment, ventilation, and ECMO therapy. Laboratory tests indicate that the immune and clotting system show marked alterations with hyper-activation, hyper-inflammation, cytokine storm development. Furthermore, organ-specific biomarkers demonstrate the involvement of cardiac muscle, kidney, and liver dysfunction in many patients. In this article the use of laboratory biomarkers is discussed with regard to their
    Document: A subgroup of COVID-19 patients develop very severe disease with requirement for ICU treatment, ventilation, and ECMO therapy. Laboratory tests indicate that the immune and clotting system show marked alterations with hyper-activation, hyper-inflammation, cytokine storm development. Furthermore, organ-specific biomarkers demonstrate the involvement of cardiac muscle, kidney, and liver dysfunction in many patients. In this article the use of laboratory biomarkers is discussed with regard to their use for diagnosis, disease progression, and risk assessment.

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