Author: Alâ€Salameh, Abdallah; Lanoix, Jeanâ€Philippe; Bennis, Youssef; Andrejak, Claire; Brochot, Etienne; Deschasse, Guillaume; Dupont, Hervé; Goeb, Vincent; Jaureguy, Maité; Lion, Sylvie; Maizel, Julien; Moyet, Julien; Vaysse, Benoit; Desailloud, Rachel; Ganry, Olivier; Schmit, Jeanâ€Luc; Lalau, Jeanâ€Daniel
Title: Characteristics and outcomes of COVIDâ€19 in hospitalized patients with and without diabetes Cord-id: 02vwdfy0 Document date: 2020_7_19
ID: 02vwdfy0
Snippet: AIMS: Coronavirus disease 2019 (COVIDâ€19) is a rapidly progressing pandemic, with four million confirmed cases and 280,000 deaths at the time of writing. Some studies have suggested that diabetes is associated with a greater risk of developing severe forms of COVIDâ€19. The primary objective of the present study was to compare the clinical features and outcomes in hospitalized COVIDâ€19 patients with vs. without diabetes. METHODS: All consecutive adult patients admitted to Amiens University
Document: AIMS: Coronavirus disease 2019 (COVIDâ€19) is a rapidly progressing pandemic, with four million confirmed cases and 280,000 deaths at the time of writing. Some studies have suggested that diabetes is associated with a greater risk of developing severe forms of COVIDâ€19. The primary objective of the present study was to compare the clinical features and outcomes in hospitalized COVIDâ€19 patients with vs. without diabetes. METHODS: All consecutive adult patients admitted to Amiens University Hospital (Amiens, France) with confirmed COVIDâ€19 up until April 21(st), 2020, were included. The composite primary endpoint comprised admission to the intensive care unit (ICU) and death. Both components were also analyzed separately in a logistic regression analysis and a Cox proportional hazards model. RESULTS: A total of 433 patients (median age: 72; 238 (55%) men; diabetes: 115 (26.6%)) were included. Most of the deaths occurred in nonâ€ICU units and among older adults. Multivariate analyses showed that diabetes was associated neither with the primary endpoint (odds ratio (OR): 1.12; 95% confidence interval (CI): 0.66â€1.90) nor with mortality (hazard ratio: 0.73; 95%CI: 0.40â€1.34) but was associated with ICU admission (OR: 2.06; 95%CI 1.09â€3.92, p=0.027) and a longer length of hospital stay. Age was negatively associated with ICU admission and positively associated with death. DISCUSSION: Diabetes was prevalent in a quarter of the patients hospitalized with COVIDâ€19; it was associated with a greater risk of ICU admission but not with a significant elevation in mortality. Further investigation of the relationship between COVIDâ€19 severity and diabetes is warranted. This article is protected by copyright. All rights reserved.
Search related documents:
Co phrase search for related documents- absence presence and acute ards: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- absence presence and local effect: 1
- absence presence and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- absence presence and long length: 1
- absence presence and low grade inflammation: 1
- actual number and acute ards: 1
- actual number and logistic regression: 1, 2
- acute ards and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute ards and low grade inflammation: 1, 2
- acute ards and low grade systemic inflammation: 1
- acute ards and low threshold: 1, 2, 3, 4, 5
- acute ards renal injury and logistic regression: 1
- local effect and logistic regression: 1, 2, 3, 4, 5
- logistic regression and long hospital stay: 1, 2, 3, 4, 5, 6, 7, 8
- logistic regression and long length: 1, 2, 3, 4
- logistic regression and low grade inflammation: 1, 2, 3
- logistic regression and low grade systemic inflammation: 1
Co phrase search for related documents, hyperlinks ordered by date